Gerardo Marín, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Osvaldo Torres-Pineda, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Carlos Castillo-Rangel, Department of Neurosurgery, Hospital Regional 1º de Octubre, Institute of Social Security and Services for State Workers (ISSSTE), Mexico City, Mexico
Dylan L. Diaz Chiguer, Department of Neurosurgery, Hospital Regional 1º de Octubre, Institute of Social Security and Services for State Workers (ISSSTE), Mexico City, Mexico
Cristofer J. Zarate-Calderon, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Juan G. Torres-Pasillas, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Iraís Viveros-Martínez, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Lizbeth Vásquez-Celaya, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Zuleyma S. Hernández Briones, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico
Helena G. Vega-Quesada, Department of Internal Medicine, General Hospital of Zone Benito Coquet Lagunes”, Monterrey N.L., Mexico
Luis A. Vega-Quesada, Department of Cardiology, Cardiology Hospital, UMAE, Monterrey N.L., Mexico
Luis I. García-Hernández, Department of Biophysics, Brain Research Institute, Xalapa, Veracruz, Mexico


Objective: It is necessary to study the main comorbidities of Parkinson’s disease that causes this increase in hospitalization. The aim of the study was to compare the mean days of hospital stay of patients with Parkinson’s disease plus a comorbidity against the mean days of hospital stay without that comorbidity and to report those which were statistically significant. Methods: Taking patients with PD from “1 de octubre” Hospital, an observational, retrospective, cross-sectional, and analytical study was carried out in which the relationship of days of hospitalization with and without comorbidities was evaluated, finding which would be the comorbidities that were they become a factor of protection or risk of prolonging the hospital stay of patients with Parkinson’s disease (PD) and thus suggest the priority of treating these conditions. Results: Of the 37 patients, 14 different comorbidities were found, of which hypothyroidism ( x = 2), acute myocardial infarction/dyslipidemia ( x = 4), and traumatic brain injury ( x = 4) present a decrease in the number of days hospitalized patients with respect to the mean of patients who do not have these comorbidities, in comparison, sacral ulcer ( x = 32.5) and pneumonia ( x = 31) show an increase in the days of hospitalization with respect to the mean. Conclusion: Fourteen comorbidities were found in PD. Patients with sacral ulcer and pneumonia are hospitalized for a longer time compared to the different comorbidities. It is recommended to pay special attention and care to prevent/treat these pathologies to reduce the number of days of hospitalization.



Keywords: Parkinson’s disease. Comorbidities. Hospitalization. Disorders. Clinical studies.